Meaning

2 senses
  1. Having difficulty with metabolism.

  2. (euphemistic, humorous)Dead.

Origin

The second sense is an ironic imitation of the perceived oversensitivity of language like

The second sense is an ironic imitation of the perceived oversensitivity of language like "mentally challenged".

Wiktionary, CC BY-SA 4.0 · source

Forms

more metabolically challenged, most metabolically challenged

See also

neighbours in the dictionary
metabolically challenged — meaning, examples, forms, synonyms | Krumeto