paroxysmal nocturnal hemoglobinuria
A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood…A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood cells to lack protective surface proteins, making them vulnerable to complement-mediated destruction, leading to hemolysis, anemia, dark urine, and increased risk of blood clots.
Meaning
1 senses(uncountable)A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood cells to lack protective surface proteins, making them vulnerable to complement-mediated destruction, leading to hemolysis, anemia, dark urine, and increased risk of blood clots.
Synonyms
1 synonymsLessons for this word
1 lessons- A1Countable and uncountable nouns — Because it can be uncountable
See also
neighbours in the dictionaryDictionary text adapted from Wiktionary (Wiktionary contributors, CC BY-SA 4.0) and Open English WordNet / Princeton WordNet (CC BY 4.0, WordNet License); shared under CC BY-SA 4.0. Example sentences and recordings are credited where they appear.